Antioxidants protect against neuronal damage induced by excitotoxins
نویسندگان
چکیده
منابع مشابه
Antioxidants protect against reoxygenation-induced cell damage in ventricular myocytes.
The process of myocardial inJury associated with oxidative cell damage is known to be related to an enhanced production of free radicals [l]. The therapeutic potential of radical scavengers has however been debated, since the damaging properties of oxygen radicals is more directed towards the formation of secondary products, including more long lasting radical species derived from superoxide an...
متن کاملDoes Ginger Protect Against Ovarian Damage in Rats Induced by Sodium Metabisulfite Toxicity? An Experimental Evidence
Background: Sulfites including sodium metabisulfite (SMB) are commonly used as food preservatives and pharmaceutical products. Despite their worldwide use, there is evidence suggesting their toxicity on human organs and tissues. The purpose of this study was to evaluate the effect of SMB with or without Zingiber officinale (ginger) extract on the rat ovary. Methods: A total of 32 adult, female...
متن کاملAntioxidants Protect against Arsenic Induced Mitochondrial Cardio-Toxicity
Arsenic is a potent cardiovascular toxicant associated with numerous biomarkers of cardiovascular diseases in exposed human populations. Arsenic is also a carcinogen, yet arsenic trioxide is used as a therapeutic agent in the treatment of acute promyelotic leukemia (APL). The therapeutic use of arsenic is limited due to its severe cardiovascular side effects. Many of the toxic effects of arseni...
متن کاملCan Antioxidants Protect Against Disuse Muscle Atrophy?
Long periods of skeletal muscle inactivity (e.g. prolonged bed rest or limb immobilization) results in a loss of muscle protein and fibre atrophy. This disuse-induced muscle atrophy is due to both a decrease in protein synthesis and increased protein breakdown. Although numerous factors contribute to the regulation of the rates of protein breakdown and synthesis in skeletal muscle, it has been ...
متن کاملLiposomal Antioxidants for Protection against Oxidant-Induced Damage
Reactive oxygen species (ROS), including superoxide anion, hydrogen peroxide, and hydroxyl radical, can be formed as normal products of aerobic metabolism and can be produced at elevated rates under pathophysiological conditions. Overproduction and/or insufficient removal of ROS result in significant damage to cell structure and functions. In vitro studies showed that antioxidants, when applied...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1990
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)55340-9